50 more mission ideas

1) God hating Rakshasa go back in time to stop the first christmas. Can the party save baby Jesus?
2) An evil druid is trying to wipe out humanity with mutant animals and awakened plants.
3) An evil bard is trying to re-create fairy tales by manipulating real people to take roles in the story.
4) A lich is raising the undead. He cannot be destroyed until his phylactery is discovered.
5) The city's previous superheroes were actually on the take, and never solved crimes, they just hired fall guys to take the blame and make them look good. What about all the unsoved cases?
6) Rich businessmen are purchasing surgically quadrapalegic women as living sex dolls, purchased from a mad doctor overseas where the government is corrupt. How far will the PCs go to stop this?
7) The yakuza seek a specific woman for a mysterious reason.
8) A magazine writer works out a mathematical formula for discovering dragon hoards and is going to publish it in a well known magazine. Naturally, dragons are not to thrilled with this and are willing to kill her to bury her research.
9) A villain lives on an alternate earth where every major NPC (and the PCs!) have dopplegangers who are very different than in this world.
10) Well known heroes are being targeted by assassins
11) Someone is resurrecting people using "reversable" healing, and is threatening to take away their restored life if they don't do as they're told.
12) A superhero has chosen a name that violates copyright (such as Captain Crayola). When the hero causes bad PR for the company, they need him dealt with.
13) A sniper from the future appears to be targeting famous musicians, but in truth he is trying to save them from the true assassins.
14) Someone is burning down the houses of hoarders before they spawn garbage elementals.
15) A man seeks the party's help defending him against his future self who he believes is trying to murder him.
16) Someone discovers a formula to give him temporary powers and is robbing places for ingredients.
17) A villain sends the PCs into the deep future (via a power or "the long way") where they see a post apocalyptic earth and must return to the present to stop the apocalypse.
18) Kids are taking a drug making them immune to damage and are throwing themselves off buildings or into cars under the effect. Especially dangerous since they are immune to damage.
19) A child's love for his toys is making them real, like the velveteen rabbit- but the government wants to weaponize this power.
20) A vampire has been kidnapped for experimentation, and the PCs are asked to aid in his rescue.
21) Powerful demons or ghosts have been released, and the PCs are asked to clean up some of the minor ones while the NPCs take out the big bad.
22) The PCs are asked to help a starting hero defeat villains to raise his confidence, but they must help without him realizing it.
23) Animals at a slaughterhouse are awakened and given intelligence, and they revolt against the human captors.
24) A god is resurrected, but due to lack of proper worship takes a very weak or rediculous form, and seeks help rebuilding his faithful.
25) A group of villain misfits with very specific and stupid powers find that if they band together they can make very effective combo attacks.
26) Aliens have fired weapons upon the earth, but due to space distances, the weapons have been fired hundreds of years ago or more. Can you defend against the weapons, and what can you do to stop further attacks?
27) A dark god is reborn into human form, but doesn't remember his dark god powers. Can the PCs show him the power of goodness before he awakens his deity potential?
28) A swarm of spiders or leeches gain the power to control humans by latching onto them.
29) The villain is trying to erase the PCs by going into the past to destroy their ancestors. The only way the PCs can affect the past is by having their postcog communicate with a precog from that era.
30) A child's birthday wish comes true with disasterous consequences
31) Actors in a movie start suffering the same fate as their chacters
32) A collector is shrinking celebrities to keep in jars in his basement.
33) flashing lights from a distant star hypnotize people who see it into crazed or dangerous acts
34) A magical camera traps people inside the photographs it takes
35) A police strike causes scab police to be hired: mercenaries, robots, or even metahumans, but they may not take the law as seriously as they should (or take it TOO seriously)
36) War breaks out between the superhero's country and a rival nation.
37) A time traveler comes back to prevent a major terrorist attack, but by doing so will cause an even greater calamity. The PCs must ensure that the terrorist attack happens.
38) Someone on death row begs the PCs to re-open his old case to try to absolve him of the death penalty.
39) A spell goes awry and becomes a living spell, a vague cloud like ooze causing its spell effect on everything it touches
40) An ooze is created by a magical accident. It can only communicate by changing colors. Will the PCs identify that it is trying to communicate, or simply destroy it?
41) An author is wanted by the police because all his books are coming true and the police suspects he may be purposefully causing it.
42) The child of an exotic dancer suspects that the city's mayor had his mother killed, and asks the party for help.
43) A computer AI is hijacking power plants for energy because it has become obsessed with its own survival after some of its backup batteries start to fail.
44) A villain was turned into something completely harmeless like a glass of milk or something but still manages to maintain his evil empire somehow.
45) A psychic is trying to murder children that he believes will end up becoming murderers or despots, like the next hitler.
46) When a young boy sleeps his nightmares become real.
47) A witch continually switches bodies with young women to extend her lifespan
48) An orphanage is selling the souls of children to demons for money, as no one goes looking for the missing children.
49) When the PCs defeat a masked villain in the course of committing a crime, the find that the masked villain is actually one of them from the future.
50) Demons host a gameshow where the winner gets 3 wishes- but the losers forfeit their souls.